Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain
- VernacularTitle:GRACE评分对急性胸痛患者30d心血管不良事件的预测价值
- Author:
Zhen-Hua HUANG
1
;
Jin-Li LIAO
;
Xiao-Yong XIAO
;
Zi YE
;
Peng JIANG
;
Wei-Dong CHEN
;
Yan XIONG
;
Zhen YANG
;
Qing-Li ZENG
;
Hong ZHAN
Author Information
1. 中山大学附属第一医院急诊科
- Keywords:
GRACE scores;
acute chest pain;
risk stratification;
cardiovascular adverse events
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2018;39(1):82-86
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To investigate the effect of GRACE scores on prediction of 30-day cardiovascular adverse events in acute chest pain patients.[Methods]A prospective,observational analysis was conducted in the patients with acute chest pain in Emergency Department(ED)from January 1,2016 through April 1,2016.Data including characteris-tics and GRACE scores were collected.All causes leading to MACE were followed up at 30th day after the onset of acute chest pain.[Results]Among a total of 209 patients presenting with acute chest pain enrolled in this study,110 were male (52.63%)and 99 were female(47.37%).The range of age was 20-98years old,and mean age was(65.28±16.85)years old.During follow-up period,12 patients had MACE,2 patients died in ED,3 patients died in hospital,6 patients died out of hospital,and 1 person was diagnosed with myocardial infarction. When compared with non-MACE group,factors including age,BMI,hospitalized patient number,and number of patients admitted in CCU as well as GRACE scores, were significantly higher in MACE group(P<0.05). The predictive ROC curve area of GRACE scores in 30-day MACE was 0.819(0.735 to 0.902). The optimal sensitivity and specificity were 0.92 and 0.65,respectively. The probability of 30-day cardiovascular adverse events in various GRACE score risk stratification was 0.95%(low-risk),6.67%(medi-um-risk),and 18.92%(high-risk),respectively.[Conclusion]The GRACE score was a useful predictor to the occur-rence of 30-day cardiovascular adverse events in acute chest pain patients.
