Analysis of influencing factors of portal vein tumor thrombus in primary liver cancer
10.3760/cma.j.issn.1006-9801.2018.09.008
- VernacularTitle:原发性肝癌门静脉癌栓形成的影响因素分析
- Author:
Jing XU
1
;
Lin TAN
;
Xuewu GAO
;
Jinling WANG
;
Fengcheng LI
Author Information
1. 236000,安徽省阜阳市第二人民医院肝脏病科二病区
- Keywords:
Liver neoplasms;
Portal vein tumor thrombus;
Alpha-fetoproteins;
Ascites
- From:
Cancer Research and Clinic
2018;30(9):610-612,616
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influencing factors of portal vein tumor thrombus in patients with primary liver cancer(PLC).Methods A total of 483 patients with PLC in the Second People's Hospital of Fuyang from January 2012 to December 2016 were included in this retrospective study.Univariate analysis and multi-variate logistic regression analysis were employed to analyze the association between portal vein tumor thrombus and routine clinical parameters.Results The univariate analysis showed that alanine aminotransferase,aspartate aminotransferase,total bilirubin,γ-glutamyltranspeptidase,alkaline phosphatase,alpha-fetoprotein,the size and the number of tumors,ascites and center location of cancer performed a close relationship with the formation of portal vein tumor thrombus in patients with PLC,and the differences were statistically significant(P values were 0.010,0.000,0.010,0.000,0.001,0.000,0.000,0.004 and 0.010).Multivariate logistic regression analysis showed that potential significant predictors of portal vein tumor thrombus in patients with PLC were alpha-fetoprotein and ascites,and the differences were statistically significant(P values were 0.000 and 0.040).Conclusion PLC patients with high level of alpha-fetoprotein and ascites are easier to induce the formation of portal vein tumor thrombus.
