Progress of bispecific antibody in cancer treatment
10.3760/cma.j.issn.1006-9801.2018.06.016
- VernacularTitle:双特异性抗体在肿瘤治疗中的研究进展
- Author:
Yaokai HU
1
;
Ningshao XIA
;
Wenxin LUO
Author Information
1. 361100,厦门大学国家传染病诊断试剂与疫苗工程技术研究中心
- Keywords:
Bispecific antibody;
Molecular targeted therapy;
Immunotherapy
- From:
Cancer Research and Clinic
2018;30(6):419-422
- CountryChina
- Language:Chinese
-
Abstract:
Bispecific antibodies can target two different targets simultaneously with a wide application prospect and rapid development in tumor treatment. The main function is to recruit effector cells selectively in order to kill tumor cells or bind tumor-associated growth factor receptor to inhibit cell proliferation. This paper reviews the current situation of bispecific antibodies in design, mechanism of action and the research progress in the clinical cancer treatment.
