Clinical observation of Shenqi Fuzheng injection combined with chemotherapy for reduction of the side effects of tumor chemotherapy
10.3760/cma.j.issn.1006-9801.2018.04.008
- VernacularTitle:参芪扶正注射液联合全身化疗减轻肿瘤化疗不良反应的临床观察
- Author:
Fang REN
1
;
Maoyun WANG
;
Gege CHEN
;
Yixin CUI
;
Haiming WANG
;
Yu FENG
;
Shaodan LI
Author Information
1. 解放军总医院中医院中医科
- Keywords:
Neoplasms;
Shenqi Fuzheng injection;
Drug therapy;
combination;
Side effect;
Quality of life
- From:
Cancer Research and Clinic
2018;30(4):251-254
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Shenqi Fuzheng injection combined with chemotherapy on reducing the side effects of malignant tumor chemotherapy. Methods Eighty cancer patients in Traditional Chinese Medicine Hospital of PLA General Hospital from January 2015 to March 2017 were randomly divided into treatment group and control group by using random number table method, each group contained 40 cases. The patients in the treatment group were given Shenqi Fuzheng injection combined with chemotherapy, while the control group used chemotherapy only. Results The incidence of WBC and Plt reduction in the treatment group [35.0 % (14/40), 32.5 % (13/40)] was lower than those in the control group [70.0 % (28/40), 57.5 % (23/40)], and the differences were statistically significant (χ 2= 9.825, P = 0.002;χ2=5.051, P=0.025). The incidence rates of digestive tract reaction and oral ulcers[52.5 %(21/40), 32.5 % (13/40)]were lower than those in the control group[75.0 %(30/40), 60.0 %(24/40)], and the differences were statistically significant (χ2= 4.381, P = 0.036; χ2= 6.084, P = 0.014). The quality of life in the treatment group was significantly improved compared with the control group [(51.4 ±5.1) points vs. (48.3±5.5) points], and the difference was statistically significant(t =2.595,P =0.011). Conclusions Shenqi Fuzheng injection combined with chemotherapy can reduce chemotherapy-induced side effects and improve the life quality of the patients.The injection can be used as the adjuvant therapy for chemotherapy in clinic application.
