Progress of vimentin in gynecological malignant tumors
10.3760/cma.j.issn.1006-9801.2018.03.017
- VernacularTitle:波形蛋白在妇科恶性肿瘤中的研究进展
- Author:
Yong ZHANG
1
;
Duo YIN
Author Information
1. 中国医科大学附属盛京医院第二微创妇科
- Keywords:
Vimentin;
Cervical neoplasms;
Endometrial neoplasms;
Ovarian neoplasms
- From:
Cancer Research and Clinic
2018;30(3):207-211
- CountryChina
- Language:Chinese
-
Abstract:
Vimentin, a kind of type Ⅲ intermediate filament protein, is the major component of cytoskeleton of stromal cells. Increasing researches have demonstrated that vimentin is over-expressed in muiltple tumor tissues, and is closely related with the occurrence, development, invasion and metastasis of tumors. However, correlated studies including cervical neoplasm, endometrial neoplasm and ovarian neoplasm start comparatively late with inconsistent conclusions, thus, a lot of mechanisms need to be further investigated. This paper reviews the expressions and the clinical significances of vimentin in 3 kinds of gynecological malignant tumors.
