Effects of acupuncture on ovarian blood supply and pregnancy outcomes in patients receiving assisted reproduction
10.1007/s1i726-018-1059-6
- VernacularTitle:针刺对接受辅助生育者卵巢血供及妊娠结局的影响
- Author:
Zheng-Zheng XU
;
Ying GAO
;
Fu-Qing ZHANG
- Keywords:
Acupuncture Therapy;
Infertility,Female;
Reproductive Technology,Assisted;
Fertilization in Vitro;
Sperm Injections,Intracytoplasmic;
Embryo Transfer;
Pregnancy Rate
- From:
Journal of Acupuncture and Tuina Science
2018;16(4):253-259
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the effects of acupuncture at the follicular phase on ovarian blood supply and pregnancy outcomes in patients who received in vitro fertilization/intracytoplasmic sperm injection-embry transfer (IVF/ICSI-ET) of assisted reproductive technology (ART).Methods:A total of 169 IVF/ICSI-ET female recipients from the Reproductive Center of Xiehe Hospital,Tongji Medical College,Huazhong University of Science & Technology were randomized into an observation group (57 cases),a placebo group (54 cases) and a control group (58 cases).The observation group received acupuncture during the follicular phase,meanwhile the placebo group received placebo-acupuncture,and the control group did not receive acupuncture.The hemodynamic index,biochemical pregnancy rate and clinical pregnancy rate of each group were observed,respectively.Results:As to the ovarian arterial hemodynamic index,the pulsatility index (PI),resistance index (RI),and the systolic-to-diastolic peak velocity ratio (S/D) of the observation group were (0.819±0.131),(0.552±0.055) and (2.306±0.512),respectively,obviously lower than those in the placebo group and the control group,and the differences were statistically significant (all P<0.05),but there were no statistically significant differences between the placebo group and the control group (all P>0.05).As to the biochemical pregnancy rate and clinical pregnancy rate,the biochemical pregnancy rate in the observation group was 64.9% and the clinical pregnancy rate was 52.6%,which were significantly higher than those in the placebo group and the control group,and the differences were statistically significant (all P<0.05),while there were no significant differences between the placebo group and the control group (both P>0.05).Conclusion:Acupuncture treatment during the follicular phase can improve ovarian blood supply and pregnancy rate in those receiving IVF/ICSI-ET.