Effectiveness analysis and inspirations of rational administration of carbapenem
10.3760/cma.j.issn.1000-6672.2018.04.012
- VernacularTitle:碳青霉烯类抗菌药物合理应用管理实效分析及思考
- Author:
Yan ZHANG
1
;
Mengjie WANG
;
Yin XU
;
Xiaozhou HE
;
Fei HUA
;
Jun ZHOU
;
Yuyue WANG
;
Chunyan QIAN
;
Lifei YANG
;
Li LI
;
Bin WANG
;
Keye TAO
;
Ling YANG
Author Information
1. 213003,常州市第一人民医院 苏州大学附属第三医院
- Keywords:
Pharmacy administration;
Carbapenem;
Antibacterial agent;
Rational use
- From:
Chinese Journal of Hospital Administration
2018;34(4):310-314
- CountryChina
- Language:Chinese
-
Abstract:
The hospital introduced a multi-department synergy in management of the rational use of carbapenems. Specifically,the medical affairs department conducts training and appraisal of doctors along with a monthly checkup of medical records. The pharmaceutical affairs division conducts prior prescriptions checkup and follow-up comment. The clinical microbiology laboratory and the hospital-acquired infection management department monitors and releases such infection and bacterial resistance information of the whole hospital in real time. The results showed increased prescriptions of imipenem and cilastatin sodium, and decreased prescriptions of biapenem for injection. Drug resistance analysis showed that carbapenem resistant strains increased by 28%,but the total number of patients reduced by 10% and total number of patients with multidrug resistance remained unchanged. It is proposed to further antimicrobial stewardship in the hospital to achieve rational drug use and curb bacterial resistance.