Current knowledge on Trichosporon spp.
10.3760/cma.j.issn.1009-9158.2018.11.019
- VernacularTitle:毛孢子菌研究进展
- Author:
Shuying YU
1
;
Li'na GUO
;
Menglan ZHOU
;
Yingchun XU
Author Information
1. 100730,中国医学科学院北京协和医学院研究生院
- Keywords:
Trichosporon;
Mycological typing techniques;
Virulence;
Microbial sensitivity tests
- From:
Chinese Journal of Laboratory Medicine
2018;41(11):883-888
- CountryChina
- Language:Chinese
-
Abstract:
In recent years , with the increasing of immunocompromised patients , Trichosporon spp. has become a more and more significant clinical opportunistic pathogen .Medical staff should enhance the clinical awareness to this pathogen . In this paper , the classification , virulence factor and pathogenic mechanism, infections, diagnostic methods of laboratory , antifungal susceptibility and treatment of Trichosporon spp. were reviewed systematically . Trichosporon asahii is the major pathogen of invasive infections.Biofilm formation and enzyme production will promote its ability to escape from antifungal drugs and host immune responses .Matrix assisted laser desorption ionization time of flight mass spectrometry has the advantages of accurate , fast and low cost for identification of Trichosporon spp., and zoles is the first-line treatment for invasive infections .
