The applications and future of emerging biomarkers in the precision diagnosis and treatment of inflammatory bowel disease
10.3760/cma.j.issn.1009-9158.2018.10.001
- VernacularTitle:新型生物标志物在炎症性肠病精准诊疗中的应用及展望
- Author:
Jie LU
1
;
Xinyou XIE
;
Jun ZHANG
Author Information
1. 310016,浙江大学医学院附属邵逸夫医院检验科
- Keywords:
Inflammatory bowel diseases;
Biomarkers;
Precision medicine
- From:
Chinese Journal of Laboratory Medicine
2018;41(10):703-707
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease is chronic intestinal inflammatory disease with unknown etiology, which may be associated with environmental , genetic and immune factors.The personalized or accurate diagnosis and treatment are a new development trend for IBD clinical management .The detection of biomarkers is very important in the diagnosis , treatment and clinical management of IBD .In addition to the traditional biomarkers , the emerging new markers based on genetics , epigenetics , microbial and metabolomics have also shown better future applications in several areas , such as the applications of biomarkers in diagnosis and differential diagnosis of IBD .The determination of disease activity , severity and complications.The selection for treatments in IBD and prediction of therapeutic effects .These biomarkers will also contribute to personalized clinical management of IBD .
