Application of terahertz spectroscopy in the detection of cell and tissue
10.3760/cma.j.issn.1009-9158.2018.05.004
- VernacularTitle:太赫兹光谱技术在细胞及组织检测中的应用
- Author:
Hao LIU
1
;
Yang ZHANG
;
Jinying DONG
;
Jiaoqi HUANG
;
Wei LIU
;
Junfu HUANG
;
Yuzhong LI
;
Weiling FU
Author Information
1. 116023,大连医科大学第二附属医院检验科
- Keywords:
Spectrum analysis;
Biosensing techniques
- From:
Chinese Journal of Laboratory Medicine
2018;41(5):348-351
- CountryChina
- Language:Chinese
-
Abstract:
As a novel,label-free and non-invasive detection modality,terahertz(THz,1THz=1012 Hz)spectroscopy has been widely used in various areas.For instance,in the biomedical field,it has great potentials to provide real-time scanning of living cells and tissues due to its unique advantages.Significant achievements have been reached in cell detection, related to bacterial identification, cancer cell characterization and blood cell detection.In tissue detection, the THz spectroscopy can be used to provide real-time scanning of living tissues and fast diagnosis.Furthermore, a single system which integrated THz spectroscopy and THz imaging would be able to collect information more sensitive and comprehensive. However,the clinical adaption of THz spectroscopy is still a controversial issue attributed to some intrinsic limitations and technical bottlenecks.In this article, both the application of THz spectroscopy in cell and tissue detection and the existing challenges and strategies to accelerate clinical applications were reviewed comprehensively.