Clinical value of bone turnover markers in the management of osteoporosis
10.3760/cma.j.issn.1009-9158.2018.04.020
- VernacularTitle:骨转换标志物在骨质疏松症管理中的临床价值
- Author:
Liyan CUI
1
;
Tianpei HONG
Author Information
1. 100191,北京大学第三医院检验科
- Keywords:
Osteoporosis;
Osteoporotic fractures;
Bone density;
Biomarkers
- From:
Chinese Journal of Laboratory Medicine
2018;41(4):333-336
- CountryChina
- Language:Chinese
-
Abstract:
Bone turnover is balanced with coupling of bone formation and resorption at various rates leading to continuous remodeling of bone.Osteoporosis diagnosis, which is nowadays generally made based on bone mineral density(BMD)measurements, suffers from certain limitations.Bone turnover markers (BTMs)can help improve osteoporosis detection.BTMs can provide information that is useful for the management of patients with osteoporosis,for assessing the possible causes of secondary osteoporosis and the correct dosage;they are also potentially useful as surrogate biomarkers for fracture.(Chin J Lab Med,2018, 41:333-336)
