The value of microecological testing on evaluation of the treatment effect of simple vulvovaginal candidiasis
10.3760/cma.j.issn.1009-9158.2018.04.011
- VernacularTitle:微生态检测在评价单纯性外阴阴道假丝酵母菌病治疗效果中的应用价值
- Author:
Xingshuo LI
1
;
Xiaobo LU
;
Mengting DONG
;
Chen WANG
;
Ye YAN
;
Fengxia XUE
Author Information
1. 300052,天津医科大学总医院妇产科
- Keywords:
Candidiasis,vulvovaginal;
Candida;
Lactobacillus;
Microbiota;
Vaginal smears
- From:
Chinese Journal of Laboratory Medicine
2018;41(4):292-295
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the value of vaginal microecological detection in evaluating therapeutic effect of simple vulvovaginal candidiasis(VVC), and explore microecological factors which can affect the cure rate of simple VVC.Methods 75 patients with simple VVC in Tianjin Medical University General Hospital from January 2016 to June 2017 were enrolled.Vaginal secretion was collected and applied for vaginal microecological detection.The patients were treated with clotrimazole based monotherapy later. The relationship between vaginal microecological characters and therapeutic effects was analyzed.Results PH values,leukocyte counts,flora density,flora diversity,small bacilli and cocci counts had no influence on therapeutic effects(P>0.05).The cure rate of patients with lactobacillary gradesⅠ-Ⅱa was higher than that with lactobacillary gradesⅡb-Ⅲ(83.33% vs 53.33%,P=0.033), while lower with lactobacilli≤22.8/hpf than that with lactobacilli >22.8/hpf(59.26% vs 87.50%,P=0.007), which indicate that lactobacilli counts was the main factor that affects therapeutic effects.Conclusions Vaginal microecological detection plays an important role in predicting the therapeutic effect of simple VVC.For the patients with lower lactobacillus counts,the follow-up after treatment should be strengthened.(Chin J Lab Med,2018, 41:292-295)
