Comparison of radiofrequency ablation and operation for overmuch residual thyroid removal before 131I treatment in differentiated thyroid cancer
10.3877/cma.j.issn.1672-6448.2018.04.009
- VernacularTitle:射频消融与手术切除在去除分化型甲状腺癌131I治疗前过多残留甲状腺组织的对比研究
- Author:
Kaiyuan SHI
1
,
2
;
Dong XU
;
Chuanming ZHENG
;
Bin LONG
;
Xiangdong YOU
Author Information
1. 310009 杭州,浙江大学医学院附属第二医院超声科
2. 310022 杭州,浙江省肿瘤医院超声科
- Keywords:
Thyroid neoplasms;
Ablation techniques;
Ultrasonography
- From:
Chinese Journal of Medical Ultrasound (Electronic Edition)
2018;15(4):281-286
- CountryChina
- Language:Chinese
-
Abstract:
Objectives The aim of this study is to compare efficacy and safety of radiofrequency ablation versus operation for overmuch residual thyroid removal before 131I treatment in differentiated thyroid cancer.Methods Clinical data from 52 newly diagnosed differentiated thyroid cancer patients who treated with operation at Zhejiang Cancer Hospital from January 2014 to December 2016 were retrospectively reviewed.The serum TSH was less than 30 IU/ml,and 99mTc thyroid imaging and ultrasound examination showed obviously residual thyroid tissue after 3 weeks of low iodine diet and discontinuation of euthyrox.Of these patients,28 cases received radiofrequency,while 24 cases treated with operation.The operation time,the waiting time of 131I treatment and the efficacy of residual thyroid tissue clearance were compared between two groups.At the same time,the complications of the two groups were observed.Results The mean values of operation time between two groups were(22.14±7.12)min and(55.45±13.56)min,respectively,and there was a statistically significant difference(t=11.822,P＜0.05).The mean waiting time of 131I treatment in patients received radiofrequency was(9.40±4.14)days,while the mean waiting time in operation group was(13.53±4.55)days,and the differences were statistically significant(t=9.144,P＜0.05).In RFA group,hoarseness,temporary parathyroid injury and permanent parathyroid injury were observed in 2 cases,0 case and 1 case,respectively.While there were 2 cases,3 cases and 0 case in the operative group.There were no significant differences between the two groups(all P ＞ 0.05).85.7%(24/28)of patients in RFA group and 91.7%(22/24)in operation group showed favorable efficacy of residual thyroid removal,and there were no significant differences between the two groups(P＞0.05).Conclusion Compared with operation,postsurgical residual thyroid tissue removal in differentiated thyroid cancer by ultrasound guided radiofrequency ablation by ultrasound guided is safe and effective,and provides a new minimally invasive treatment for patients who are reluctant to undergo surgery.
