Value of color Doppler ultrasonography in the evaluation of retinoblastoma
10.3877/cma.j.issn.1672-6448.2017.10.002
- VernacularTitle:彩色多普勒超声在视网膜母细胞瘤诊断中的应用价值
- Author:
Rui CUI
1
;
Dongjun LI
;
Ziyang WANG
;
Wei CHEN
;
Qi ZHAO
;
Yifeng LI
;
Lin SHEN
;
Wenli YANG
Author Information
1. 100730,首都医科大学附属北京同仁医院 北京同仁眼科中心 北京市眼科学与视觉科学重点实验室
- Keywords:
Retinoblastoma;
Ultrasonography,Doppler,color;
Diagnosis
- From:
Chinese Journal of Medical Ultrasound (Electronic Edition)
2017;14(10):725-729
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of color Doppler ultrasonography in the diagnosis of retinoblastoma (RB). Methods One hundred and eighty-two patients (199 eyes) with RB confirmed by pathology from June 2012 to June 2016 in Beijing Tongren Hospital were included in this study. The two-dimensional gray-scale image and color Doppler imaging ultrasound features were observed. The variance analysis was used to compare the width and height of different morphologies. Comparison the detection rate of the two methods by χ2test.Results The ultrasonography of RB was characterized by substantial masses of the eyeball, which could be hemispherical, spherical, irregular, filled with vitreous cavity, or diffuse along the retina. The results of variance analysis showed statistical difference in three shapes (F= 29.134, 24.474, P<0.001),LSD-t test showed difference between hemisphere and spherical,spherical and irregular shape, hemispherical and irregular shape. The t values of basal width were 2.457,-2.333 and-6.205, respectively and all P < 0.05 respectively. The t value of height were 3.917,-6.711 and-7.244, respectively and all P < 0.05.All lesions were uneven echo. Calcification and localized low echo area within the mass was observed in 93.47% (186/199) and 52.76% (105/199) eyes respectively. 46.73% (93/199) retinal detachment and 31.16% (62/199) vitreous opacity is present. Colorful blood flow signals extended from the central retinal vessels could be seen inside the masses of 98.49% (196/199) eyes. Two-dimensional image and color Doppler imaging ultrasound were consistent with the pathological diagnosis in 96.5% (192/199) and 99.5% (198/199) RB cases, respectively.The difference was statistically significant (χ2=4.167, P=0.031). Conclusions Retinoblastoma has characteristic ultrasound manifestations. Color Doppler ultrasonography is a valuable clinical tool in the diagnosis of RB.
