Effect of retinal hemorrhage on laser photocoagulation in patients with retinopathy of prematurity
10.3760/cma.j.issn.1005-1015.2018.05.011
- VernacularTitle:视网膜出血对早产儿视网膜病变激光光凝治疗后疗效的影响
- Author:
Ruyin TIAN
1
;
Guoming ZHANG
;
Honghui HE
;
Zhenquan WU
;
Jinfeng ZHAO
Author Information
1. 518040,深圳市眼科医院深圳市眼科学重点实验室暨南大学附属深圳眼科医院
- Keywords:
Retinopathy of prematurity/therapy;
Retinal hemorrhage;
Laser coagulation
- From:
Chinese Journal of Ocular Fundus Diseases
2018;34(5):467-470
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of retinal hemorrhage on the treatment of retinopathy of prematurity (ROP) by laser photocoagulation.Methods Retrospective case analysis.Screening and diagnosis of 134 eyes in 67 patients with ROP in Zone IⅡ Stage 3+ were included in the study.Among them,32 patients were male and 35 patients were female.The average birth gestational age was 27.80 ± 2.55 weeks.The average birth weight was 1060± 320 g.All children underwent binocular indirect ophthalmoscopy and RetCam Ⅲ.Of the 134 eyes,38 eyes (28％) with anterior,ridge or vitreous hemorrhage (group A);96 eyes (72％) without hemorrhage.Retinal avascular photocoagulation was performed within 72 hours after diagnosis by intravenous sedative combined with ocular surface anesthesia with 810 nm laser.Follow-up was performed at 1,4,8 and 12 weeks after treatment,and then every 6 months thereafter.The same equipment and methods before treatment were used to examine and document the regression and progression of ROP.The number of eyes with lesions after photocoagulation in the two groups was compared by x2 test.The t-test was used to compare the gestational age and birth weight.Results Among 134 eyes,lesions completely resolved in 125 eyes (93.3％),progressed in 9 eyes (6.7％).In group A,7 eyes were progressive (18.4％).In group B,2 eyes were progressive (2.1％).There was a statistically significant difference in the number of eyes with lesions after laser treatment in group A and B (x2=9.14,P=0.003).There was no significant difference in birth gestational age and birth weight (t=0.85,0.25;P=0.40,0.80).Conclusion The laser photocoagulation is safe and effective in the treatment of ROP.The preretinal,ridge or vitreous hemorrhage is related to the progression of the lesion after laser photocoagulation.
