Observation of choroidal blood flow and morphology in patients with severe stenosis of internal carotid artery
10.3760/cma.j.issn.1005-1015.2018.01.008
- VernacularTitle:颈内动脉重度狭窄患者脉络膜血流及形态结构观察
- Author:
Hui WANG
1
;
Hongyang LI
;
Lu ZHAO
;
Xi CHEN
;
Xiaoxiao GUO
;
Jiao SUN
;
Yanling WANG
;
Ran YOU
Author Information
1. 100050,首都医科大学附属北京友谊医院眼科
- Keywords:
Carotid stenosis;
Choroid;
Regional blood flow;
Tomography;
optical coherence;
Ultrasonography;
Doppler;
color
- From:
Chinese Journal of Ocular Fundus Diseases
2018;34(1):29-33
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the choroidal blood flow and morphological changes in patients with severe stenosis of internal carotid artery stenosis (ICAS).Methods A retrospective case-control study. Forty-six patients (46 eyes) with ICAS were enrolled in this study. There was severe stenosis in one side (the eyes in this side were set as case group) and mild or no stenosis in other side (the eyes in this side were set as control group). Color doppler ultrasound (CDI) was used to observe the changes of hemodynamic parameters of the ophthalmic artery (OA) and posterior ciliary artery (PCA),the main parameters of ultrasound Doppler imaging are peak systolic velocity (PSV), end diastolic velocity (EDV), resistance indices (RI) and the calculation of the pulsation indices (PI) through the use of a formula. Enhanced binarization of deep imaging coherence tomography (EDI-OCT) was used to measure the subfoveal choroidal thickness (SFCT). The total subfoveal choroidal area (TCA), luminal (LA), stromal (SA) and choroidal vascularity index (CVI) were obtained by modified image binarization technique.Results In the case group, the PSV in the OA and PCA was significantly lower than that of the control group (t=?2.200, ?2.612;P=0.030, 0.011). There were no significant differences in EDV, RI, PI of OA (t=0.337, ?1.810, ?1.848;P=0.737, 0.074, 0.068) and PCA (t=?1.160, 1.400, 0.815;P=0.249, 0.165, 0.417). The SFCT (t=?3.711,P<0.001), TCA (t=?2.736,P=0.007), LA (t=?3.188, P=0.002) and CVI (t=?2.096,P=0.039) of the case group was significantly lower than that of the control group. There were no significant differences in SA (t=?1.262,P=0.210) and LA/SA (t=?1.696,P=0.093).Conclusion In severe stenosis ICAS eyes, the PSV in the PCA and SFCT, TCA, LA, CVI are decreased.
