Inadequate energy and protein supply in children undergoing cardiopulmonary bypass surgery:current problems and future direction
10.3760/cma.j.issn.1001-4497.2018.05.016
- VernacularTitle:先天性心脏病患儿术后早期能量和蛋白质供给不足:障碍及发展方向
- Author:
Jian ZHANG
1
;
Yanqin CUI
;
Zeming MA
;
Yi LUO
;
Xinxin CHEN
;
Jia LI
Author Information
1. 100020,首都儿科研究所病理生理实验室
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2018;34(5):317-320
- CountryChina
- Language:Chinese
-
Abstract:
Objective It has been increasingly realized that perioperative nutritional support plays an important role in improving clinical outcomes in children with congenital heart disease ( CHD) undergoing cardiopulmonary bypass surgery.The purpose of this review was to examine the nutritional conditions in perioperative CHD children and the main problems in nutri-tional management in the cardiac intensive care unit ( CICU) , based on which further directions were proposed .We found that preoperative malnutrition is common .This limited research of energy and protein is further compounded by the complex meta-bolic alterations with hyper-metabolism, hyper-catabolism and hypo-anabolism in the early postoperative course.Knowledge a-bout energy and protein metabolism and requirements in post-CPB children remains much limited .The current nutritional rec-ommendations in the CICU are based on little evidence .Insufficient energy and protein supply to meet demands remains a norm in the immediate postoperative period .The commonly used predictive equations do not provide accurate estimate of energy re-quirement in individual patients during the highly dynamic postoperative course .Indirect calorimetry can provide the best esti-mate of energy requirements for CHD infants .Nitrogen balance is recommended to assess the minimal protein requirement . During the early postoperative period, daily measurements of resting energy expenditure using indirect calorimetry and nitrogen balance in each individual child are essential to optimize energy and protein supply to meet requirements .A paradigm should be shifted toward individualized nutrition prescription in the context of a specific CICU feeding algorithm .
