Clinical characteristics and prognosis of patients with rectal gastrointestinal stromal tumor
10.3760/cma.j.issn.1007-5232.2018.09.008
- VernacularTitle:直肠间质瘤的临床特征及预后分析研究
- Author:
Mengyue JI
1
;
Dongtao SHI
;
Duanmin HU
;
Deqing ZHANG
;
Rui LI
;
Bing WU
;
Weichang CHEN
Author Information
1. 苏州大学附属第一医院消化内科
- Keywords:
Gastrointestinal stromal tumors;
rectal;
Clinical characteristic;
Therapy;
Prognosis
- From:
Chinese Journal of Digestive Endoscopy
2018;35(9):638-643
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical characteristics and prognosis of patients with rectal gastrointestinal stromal tumor ( GIST) . Methods We collected the data of 31 rectal GIST patients definitely demonstrated by pathology and immunohistochemistry in the First Affiliated Hospital of Soochow University, the Second Affiliated Hospital of Soochow University, and Suzhou Wuzhong People′s Hospital from January 2008 to December 2016. The clinical characteristics, therapeutic modalities, and prognoses were retrospectively analyzed. Results Among the 31 rectal GIST patients, 16 underwent local resection and 15 underwent radical surgery. There was no significant difference on the three-year survival rate between the two groups [ 93. 8％ ( 15/16 ) VS 73. 3％ ( 11/15 ) , P=0. 135 ] . There was no significant difference on the survival rate between the oral imatinib patients and non-oral imatinib patients in the local resection group [ 75. 0％ ( 3/4) VS 100. 0％ ( 12/12) , P=0. 083] and the radical surgery group[ 77. 8％ ( 7/9) VS 66. 7％(4/6), P=0. 579]. The postoperative recurrence and metastasis rate of the two groups was no significantly different[31. 3％ (5/16) VS 53. 3％ (8/15), P=0. 213]. Conclusion The choice of surgical procedure has no significant effects on the survival rate and postoperative recurrence for rectal GIST patients, and whether oral imatinib or not has no significant effects on the survival of patients.
