Clinical features and pathology of 7408 colorectal lessions based on colorectal cancer screening
10.3760/cma.j.issn.1007-5232.2018.09.006
- VernacularTitle:结直肠癌筛查发现的7408例肠道病变临床特征及病理类型分析
- Author:
Panxuan CAO
1
;
Yongzhou SHEN
;
Yanqin HUANG
;
Chunxiao JIANG
;
Haoqing MA
;
Zhengyuan WANG
Author Information
1. 314400,浙江省海宁市中医院肛肠外科
- Keywords:
Colorectal neoplasms;
Colonic polyps;
Screening;
Pathology;
clinical
- From:
Chinese Journal of Digestive Endoscopy
2018;35(9):630-633
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical and pathological features of patients with colorectal lesions, which could be the basis for clinical diagnosis and treatment of early colorectal cancer. Methods The clinical ( including gender, age, size, location, morphology, and number ) and pathological characteristics of colorectal lesions were discussed based on the results of colorectal cancer screening in more than 320000 people of 40-74 years in Haining from 2007 to 2012. Results Screening of 286470 cases were completed with the compliance rate of 88. 96%. Colonoscopy was performed in 29069 cases, and 7408 lesions were detected with detection rate of 25. 48%. The detection rate was 32. 62% for men and 19. 48% for women ( P<0. 001 ) , and 18. 30% in 40-49 age group and 35. 06% in 70-74 age group. The older the patients, the higher the detection rate ( P<0. 001) . Among the 7408 lesions, left colonic lesions accounted for 69. 40%, multiple lesions accounted for 37. 23%, lesions with diameter>1. 0 cm accounted for 19. 60%. A total of 205 cases of colorectal cancer ( including 161 early carcinoma and 44 advanced carcinoma) , and 1365 cases of advanced adenoma were found. The early diagnosis rate was 97. 20%. Among the 5030 lesions underwent treatment, adenomatous and carcinomatous types accounted for the largest proportion ( 63. 00%) . The canceration rate of lesions with diameter >1. 5 cm was 34. 08%. Conclusion In high-risk populations, men have a higher detection rate of colorectal lesion than female. The older the age, the higher the detection rate. Adenoma account for the highest proportion among different pathologic types.