Long-term efficacy of peroral endoscopic circular myotomy and full-thickness myotomy on treatment of achalasia of cardia
10.3760/cma.j.issn.1007-5232.2018.05.006
- VernacularTitle:环形肌切开和全层肌切开治疗贲门失弛缓症的长期随访研究
- Author:
Dezhi HE
1
;
Juan WANG
;
Yanmiao HAN
;
Jiansheng LI
;
Xiaotong WANG
;
Pu ZHENG
;
Yanyan ZHENG
;
Yang CHEN
;
Shuguan WANG
Author Information
1. 郑州大学第一附属医院消化内科 河南省高等学校临床医学重点学科开放实验室
- Keywords:
Achalasia,cardia;
Peroral endoscopic myotomy;
Circular myotomy;
Full-thickness myotomy;
Long-term efficacy
- From:
Chinese Journal of Digestive Endoscopy
2018;35(5):327-331
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the long-term efficacy and complications of peroral endoscopic circular myotomy and full-thickness myotomy for patients with achalasia of cardia. Methods A retrospective analysis was performed on the data of 53 patients with achalasia of cardia, who underwent peroral endoscopic myotomy in the First Affiliated Hospital of Zhengzhou University from June 2012 to December 2014 and were followed-up regularly.Twenty-one patients underwent circular myotomy, and the other 32 patients underwent full-thickness myotomy. The postoperative long-term efficacy and gastroesophageal reflux complications of the two groups were compared. Results The effective rate of the circular myotomy group and the full-thickness myotomy group was 90. 5%( 19/21) and 100. 0%( 32/32), respectively ( P＝ 0. 152). There were no significant differences between the two groups on postoperative Eckardt scores, lower esophageal sphincter pressure and 4 s integrated relaxation pressure ( P ＞ 0. 05 ). The incidence of clinically relevant gastroesophageal reflux of full-thickness myotomy group was higher than that of circular myotomy group (40. 6% VS 14. 3%, χ2＝4. 174, P＝0. 041). Conclusion The long-term efficacy of circular myotomy is similar to that of full-thickness myotomy, but the incidence of clinically relevant gastroesophageal reflux is higher in full-thickness myotomy.
