Long-term effect of fully covered metal stents on benign bile duct stenosis
10.3760/cma.j.issn.1007-5232.2018.01.010
- VernacularTitle:采用全覆膜金属支架治疗良性胆管狭窄的远期疗效观察
- Author:
Yechen WU
1
;
Xiao ZHENG
;
Jun WU
;
Tiantian WANG
;
Mingxing XIA
;
Daojian GAO
;
Tingting FAN
;
Lei LIANG
;
Xiaoyong LI
;
Bing HU
Author Information
1. 苏州大学研究生院
- Keywords:
Cholangiopancreatography;
endoscopic retrograde;
Benign bile ductstenosis;
Fully covered expandable metal stent;
Efficiency;
long-term
- From:
Chinese Journal of Digestive Endoscopy
2018;35(1):49-54
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the long-term outcome of fully covered self-expandable metal stents(FCSEMS)for the treatment of benign biliary strictures(BBS). Methods Between June 2008 and September 2013, 68 patients with BBS receiving endoscopic retrograde cholangiopancreatography and FCSEMS placement were retrospectively enrolled. Data of endoscopic treatment, stricture resolution and recurrence were collected, and related risk factors were analyzed. Results FCSEMSs were successfully placed in all patients and removed in 93.4%(57/61). The median stent duration was 9.0(range 0.2-37.1)months. Stricture resolution occurred in 74.2%(46/62)patients. During median follow-up of 54.0 (range 2.5-96.0)months,stricture recurrences were seen in 16.7%(6/36)patients. Multivariate analysis revealed that distance between stricture and hepatic bifurcation of less than 1.5 cm(P=0.034,OR=6.395, 95%CI:1.153-35.464), and stent migration(P= 0.024, OR= 0.153, 95%CI:0.030-0.782)were significant risk factors for stricture resolution. Meanwhile, the stricture length longer than 1.0 cm(P=0.028, HR = 6.766, 95% CI:1.233-37.122)was a significant risk factor for stricture recurrence. Conclusion Endoscopic treatment combined with FCSEMS can achieve excellent efficacy in resolving BBS with low recurrence rate. However, location and length of BBS, as well as stent migration may impair its effectiveness.
