Effects of different injection methods of nanocarbon tracer on gastrectomy for patients with gastric cancer
10.3760/cma.j.issn.1007-5232.2018.01.007
- VernacularTitle:不同方法注射纳米碳示踪剂在胃癌根治术中的效果研究
- Author:
Xiaojian HE
1
;
Gang LIU
;
Xiaolan ZHANG
;
Wen WANG
;
Zhijian ZHANG
;
Kerong LIN
;
Dazhou LI
;
Rong WANG
;
Jianqiang LIU
;
Wulian LIN
Author Information
1. 福州总医院 厦门大学附属东方医院 福建医科大学福总临床医学院消化内科
- Keywords:
Stomach cancer;
Nanocarbon;
Lymph node trace
- From:
Chinese Journal of Digestive Endoscopy
2018;35(1):37-40
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss effects of different injection methods of nanocarbon tracer on gastrectomy for patients with gastric cancer. Methods Patients, who underwent D2 gastrectomy in Fuzhou General Hospital from January 2014 to December 2015, were randomly divided into group A and group B. The patients in group A were injected with nanocarbon into gastric submucosa of peripheral area of tumor under gastroscope 24 hours before operation. The patients in group B were injected with normal saline firstly, and then injected with nanocarbon. The operations were performed by 5 high qualification physicians and 3 low qualification physicians. The detection of lymph nodes and black stain nodes,detection time,and lymph node metastatic rate were compared between the two groups.Results A total of 248 patients were enrolled in this study,and each group had 124 cases. There was no statistical difference on basic characteristics between the two groups(P>0.05). A total of 2 975 and 3 855 lymph nodes were detected in group A and group B, respectively. The mean number of detected lymph nodes in group A was significantly lower than that of group B(23.9±7.9 VS 31.1±3.6, P=0.00). The rate of black stain nodes in group A was significantly lower than that of group B[71.3%(2 121/2 975)VS 78.1%(3 011/3 855), P= 0.00].There were no statistical differences on lymph node detection time(24.3±5.7 min VS 23.5±6.2 min), tiny lymph node detection rate(33.1% VS 34.9%),and lymph node metastatic rate(27.3% VS 25.8%)between the two groups(P>0.05).In subgroup of low qualification physicians, the number of lymph nodes(16.9± 4.0 VS 30.1±3.7)and the rate of black stain nodes(61.3% VS 77.2%)in group A were significantly lower than those of group B(P<0.05). The corresponding indicators(31.1±3.3 VS 31.5±3.5,76.8% VS 79.0%) had no statistical differences in the subgroup of high qualification physicians(P>0.05). Conclusion For low qualification physicians, injection of normal saline then of nanocarbon into gastric submucosa under gastroscope could improve lymph node and black stain nodes detection rate for patients with gastric cancer on gastrectomy.
