- Author:
Won Il JEONG
1
;
Sun Hee DO
;
Da Hee JEONG
;
Jae Yong CHUNG
;
Hai Jie YANG
;
Dong Wei YUAN
;
Il Hwa HONG
;
Jin Kyu PARK
;
Moon Jung GOO
;
Kyu Shik JEONG
Author Information
- Publication Type:Case Report ; Research Support, Non-U.S. Gov't
- Keywords: canine renal failure syndrome; fungal toxin; kidney; nephrolith
- MeSH: Animals; Dog Diseases/microbiology/*pathology; Dogs; Fatal Outcome; Female; Histocytochemistry/veterinary; Kidney Failure, Acute/microbiology/pathology/*veterinary; Male; Mycotoxicosis/microbiology/pathology/*veterinary
- From:Journal of Veterinary Science 2006;7(3):299-301
- CountryRepublic of Korea
- Language:English
- Abstract: Three dead dogs were brought to the College of Veterinary Medicine, Kyungpook National University for study. Clinically, all the dogs showed emaciation, anorexia, depression, hemorrhagic vomiting and diarrhea for 7~10 days before death. All the clinical signs were first noted for about one month after feeding the dogs with commercial diets. At necropsy, all 3 dogs had severe renal damage with the same green-yellowish colored nephroliths in the renal pelvis. They also showed systemic hemorrhage and calcification of several organs, which might have been induced by uremia. Microscopically, necrosis, calcification and calculi were detected in the renal tubules, and especially in the proximal convoluted tubules and collecting ducts of the kidney. These findings were supportive of a mycotoxic effect, and especially on their kidneys. However, the precise cause of the toxic effect in these cases of canine renal failure could not be determined.