Correlation between intestinal microbiota and immune response to vaccination
10.3760/cma.j.issn.0254-5101.2018.03.013
- VernacularTitle:肠道微生物群与疫苗免疫应答相关性的临床研究进展
- Author:
Siyue JIA
1
;
Jingxin LI
;
Fengcai ZHU
Author Information
1. 211166,南京医科大学公共卫生学院
- Keywords:
Intestinal tract;
Microbiota;
Vaccine;
Immune response
- From:
Chinese Journal of Microbiology and Immunology
2018;38(3):237-240
- CountryChina
- Language:Chinese
-
Abstract:
Intestinal microbiota plays an important role in the development of immune system,es-pecially in the formation of immune response. Immune response to vaccination varies with region and popula-tion,which may be related to the differences in intestinal microbiota. This review focused on the correlation between intestinal microbiota and immune response to vaccination in order to find a new way to enhance vac-cine-induced immune response. It was revealed that intestinal microbiota might be involved in the immune responses to vaccines against rotavirus, typhoid and polio. Although probiotics, prebiotics and synbiotics could not significantly enhance vaccine-induced immune response,they might have a beneficial effect on vac-cine by regulating intestinal microbiota.
