Incidence and risk factors of left ventricular hypertrophy in peritoneal dialysis patients with different hydration statuses

Feng LI; Xinyu SU; Miao Liu; Hao Yan; Zhenyuan LI; Yiwei Shen; Jiangzi Yuan; Zhaohui NI; Wei Fang

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Incidence and risk factors of left ventricular hypertrophy in peritoneal dialysis patients with different hydration statuses

VernacularTitle:不同容量负荷腹膜透析患者左心室肥厚发生率及相关危险因素
Author: Feng LI ^{1
,

2} ; Xinyu SU ; Miao LIU ; Hao YAN ; Zhenyuan LI ; Yiwei SHEN ; Jiangzi YUAN ; Zhaohui NI ; Wei FANG
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1. 200127 上海交通大学医学院附属仁济医院肾脏内科上海市腹膜透析研究中心
2. 上海市嘉定区中心医院肾脏内科
Keywords: Peritoneal dialysis; Edema; Hypertrophy,left ventricular; Bioelectrical impedance
From: Chinese Journal of Nephrology 2018;34(2):81-86
CountryChina
Language:Chinese
Abstract: Objective To investigate the incidence of left ventricular hypertrophy (LVH) in peritoneal dialysis (PD) patients with different hydration statuses,and analyze the risk factors of LVH in PD patients.Methods PD patients in Renji Hospital,Shanghai Jiao Tong University School of Medicine from September 2016 to January 2017 were enrolled.Demographic data of patients were collected and biochemical parameters were measured.Hydration status index overhydration (OH) was measured by bioimpedance spectroscopy,and LVH was diagnosed by echocardiography.Logistic regression was used to analyze the risk factors of LVH.Results A total of 113 PD patients aged 58.98(48.89,65.33) years with median PD duration 46.20(18.08,72.75) months were enrolled in present study,among whom 60 patients (53.1％) had LVH.OH ＞ 1.1 L was detected in 80 patients (70.8％),among whom 34 patients (42.5％) had subclinical overhydration (SCOH).LVH was however diagnosed in 33(71.7％) clinical overhydrated (COH) patients and 17(50.0％) SCOH patients (n=34).In the normal hydrated (OH≤1.1 L) patients (n=33),LVH was detected in 10 patients (30.3％).Multivariate logistic regression showed that high OH (OR=1.730,95％CI 1.274-2.348,P ＜ 0.001) and low hemoglobin (OR=0.965,95％CI 0.940-0.991,P=0.008) were the independent risk factors of LVH.Conclusions LVH is common in PD patients,especially in overhydrated patients.High OH and low hemoglobin were the independent risk factors of LVH.