Neuromyelitis optica spectrum disorder associated with herpes zoster:a case report
10.3760/cma.j.issn.1006-7876.2018.11.011
- VernacularTitle:带状疱疹病毒感染后视神经脊髓炎谱系疾病一例
- Author:
Guanen ZHOU
1
;
Yunyan HE
;
Zhongping AN
Author Information
1. 300350,天津市环湖医院神经内科
- Keywords:
Neuromyelitis optica;
Herpes zoster;
Aquaporin-4
- From:
Chinese Journal of Neurology
2018;51(11):908-911
- CountryChina
- Language:Chinese
-
Abstract:
We report here a case of myelitis of the cervical spinal cord in a 59-year-old woman presented with right arm weakness and numbness. Cervical myelitis developed three weeks after the eruption of zoster rash from the C2 to C5 dermatomes. The serum aquaporin-4 antibody was detected using the cell based transfection immunofluorescence assay. MRI of the cervical spine revealed abnormal cord signal. Cerebrospinal fluid analysis demonstrated varicella-zoster virus DNA was not detected. The patient was diagnosed with neuromyelitis optica spectrum disorder, supporting the hypothesis that the pathogenesis of neuromyelitis optica spectrum disorders is triggered by infection.
