Clinical characteristics of four patients with primary intraspinal lymphoma
10.3760/cma.j.issn.1006-7876.2018.04.009
- VernacularTitle:原发性椎管内淋巴瘤四例临床特点分析
- Author:
Hong YANG
1
,
2
;
Weizhou ZANG
;
Mingrong XIA
;
Yajing SUN
;
Jiewen ZHANG
Author Information
1. 453003 河南省新乡医学院
2. 河南省人民医院神经内科
- Keywords:
Spinal canal;
Lymphoma,non-Hodgkin;
B-lymphocytes;
Magnetic resonance imaging;
Biopsy
- From:
Chinese Journal of Neurology
2018;51(4):288-293
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze clinical characteristics of four cases with primary intraspinal lymphoma to achieve early diagnosis of the disease.Methods Clinical data including the clinical presentation,imaging features and pathological characteristics of four patients diagnosed as primary intraspinal lymphoma confirmed surgically and pathologically from February 2014 to February 2017 in Henan Provincial People's Hospital were analyzed retrospectively,and literatures were reviewed.Results The major clinical manifestations of the primary intraspinal lymphoma were as following:persistent or intermittent waist (back) pain,accompanied with both lower limb weakness,dysfunction of motion,loss or disappearance of sensation,incontinence,followed by an acute progressive neurological function deterioration.The imaging showed a single fusiform shape or irregular lump.The T1 WI signal was equal or slightly lower,and T2WI showed equal or slightly higher signal,and the general signal uniform;The lump showed mild or moderate homogeneous enhancement.The group of four cases were B cell non-Hodgkin lymphoma confirmed by pathological biopsy.Conclusions The clinical and imaging features of primary intraspinal lymphoma are lack of specificity and are easy to be misdiaguosed.The diagnosis is mainly based on pathological biopsy.
