Association between blood cell ratios and lower extremity arterial ultrasonography abnormalities in patients with type 2 diabetes mellitus
10.3760/cma.j.issn.1671-7368.2018.12.012
- VernacularTitle:2型糖尿病患者下肢动脉彩超异常与血细胞比值的相关性研究
- Author:
Yuhong LI
1
;
Yu CHEN
;
Zhenqian FAN
;
Jianchao GUO
Author Information
1. 300211,天津医科大学第二医院内分泌科
- Keywords:
Diabetes mellitus;
type 2;
Peripheral vascular diseases;
lower extremity;
Blood cell count
- From:
Chinese Journal of General Practitioners
2018;17(12):1009-1012
- CountryChina
- Language:Chinese
-
Abstract:
Clinical data of 380 patients with type 2 diabetes mellitus (T2DM) admitted in the Second Hospital of Tianjin Medical University from October 2014 to June 2017 were retrospectively reviewed. Patients were divided into 3 groups according to the results of lower extremity arterial ultrasonography: 103 patients without lower extremity arterial disease (group A), 132 patients with mild arterial disease (group B), 145 patients with moderate to severe lower extremity arterial disease (group C);and 100 healthy subjects served as control group. Blood routine parameters and blood biochemistry were measured;the results showed that blood cell ratios in T2DM patients were significantly higher than those in control group (P<0.05), and blood cell ratios in group B and group C were higher than those in group A (P<0.05). Pearson correlation analyses indicated that neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), hs-CRP, HbA1c, LDL-C were significantly associated with lower extremity arterial disease in T2DM patients. Logistic analysis showed that NLR(OR=2.01,95％CI:1.15-3.63,P<0.05)and PLR(OR=1.75,95％CI:1.04-3.28,P<0.05)were risk factors for lower extremity arterial disease in patients with type 2 diabetes mellitus.
