Recent progress of vitamin C in management of sepsis
10.3760/cma.j.issn.1671-7368.2018.10.021
- VernacularTitle:维生素C在脓毒症治疗中的应用研究进展
- Author:
Shimin LU
1
;
Shan TIAN
;
Weiguo DONG
Author Information
1. 430060,武汉大学人民医院消化内科
- Keywords:
Sepsis;
Ascorbic acid;
Antioxidants
- From:
Chinese Journal of General Practitioners
2018;17(10):827-829
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is frequently associated with multi-system organ dysfunction and refractory hypotension,leading to a high mortality and poor prognosis.As an antioxidant,ascorbic acid (vitamin C) is an important auxiliary factor for many enzymes in the organism.Numerous studies have revealed that vitamin C can attenuate the inflammatory response,improve microcirculatory and hypotension in sepsis,and also can enhance the role of catecholamine in central nervous system,to prevent sepsis-induced organ failure and improve prognosis of patients.
