Transient elastography in diagnosis of non-alcoholic fatty liver disease

VernacularTitle:瞬时弹性成像技术对非酒精性脂肪性肝病的诊断及相关因素分析
Author: Xiuzhen YANG ¹ ; Li XIAO ; Jianchun XIAN ; Lili ZHANG ; Wei WANG ; Aiwen GENG ; Lixin YU
Author Information

1. 225300,江苏省泰州市人民医院肝病科
Keywords: Fatty liver,non-alcoholic; Ultrasonograph; Elasticity imaging techniques
From: Chinese Journal of General Practitioners 2018;17(7):548-550
CountryChina
Language:Chinese
Abstract: Clinical data of 113 patients with non-alcoholic fat liver disease (NAFLD) diagnosed by liver biopsy from January 2015 to January 2017 in Taizhou People's Hospital were retrospectively reviewed . Patients all underwent transient elastographic ( TE) examination and the values of fat attenuation index (FAI) were obtained.The hepatocyt fatty changes in pathological examination were scored as 0 (＜5%, n＝40), 1 (5%-33%,n ＝27), 2 (34% -66%,n ＝28) and 3 (＞66%, n ＝18).There were significant differences in AST , Glu, TC and FAI among patients with hepatocyte fatty change scores 0, 1, 2 and 3, and the FAI was significantly correlated with the degree of fatty liver disease .The areas under the ROC curve (AUCs) of FAI in patients with hepatocyte fatty change scores 1, 2 and 3 were 0.78, 0.90 and 0.96, respectively.Logistic regression analysis showed that FAI was correlated with TG , TC and BMI.The results suggest that FAI in TE can be a non-invasive, rapid and objective evaluation method for patients with NAFLD.