Hemoglobin level is a risk factor of non-alcoholic fatty liver disease

VernacularTitle:血红蛋白水平与非酒精性脂肪性肝病发生风险相关性队列研究
Author: Annan LIU ^{1
,

2} ; Jie PAN ; Leilei WANG ; Shuwen YANG ; Yan ZHANG ; Jing FU ; Suyan CAO
Author Information

1. 100730 北京医院特需医疗部
2. 国家老年医学中心
Keywords: Fatty liver; Hemoglobins; Cohort studies
From: Chinese Journal of General Practitioners 2018;17(2):130-132
CountryChina
Language:Chinese
Abstract: Total 732 subjects aged 30-60 years undergoing health check-up at Beijing Hospital Medical Examination Center in 2009,who had no history of non-alcoholic fatty liver disease (NAFLD) were recruited in the study.According to the quartile of hemoglobin (HGB) level,the subjects were divided into 4 groups:Q1:HGB ≤ 131 g/L (n =192),Q2:HGB ＞ 131 g/L and ≤ 140 g/L (n =178),Q3:HGB ＞ 140 g/L and ≤152 g/L (n =184),Q4:HGB ＞ 152 g/L (n =178).All participants were followed up for 4 years,the prevalence rates of NAFLD in groups Q1,Q2,Q3 and Q4 were 8.3％ (16/192),17.4％ (31/178),23.4％ (43/184) and 25.3％ (45/178),respectively (P ＜0.05).Logistic regression showed that the rates of NAFLD in groups Q2,Q3 and Q4 were 2.32 (1.22-4.41),3.36 (1.81-6.21) and 3.72(2.02-6.87) times higher as group Q1 (P ＜ 0.05).Multiple logistic regression analysis showed that the hemoglobin level,TG and BMI were the independent risk factors of NAFLD.