Distribution and therapy strategy of culture microorganisms of kidney perfusion fluid
10.3760/cma.j.issn.0254-1785.2018.03.002
- VernacularTitle:供肾灌注液培养微生物分布及治疗对策
- Author:
Liang TAN
1
;
Xubiao XIE
;
Longkai PENG
;
Fenghua PENG
;
Gongbin LAN
;
Shaojie YU
;
Yu WANG
;
Xiaotian TANG
;
Chunhua FANG
;
Manhua NIE
;
Feng LIU
;
Mingjie XU
;
Lei SONG
Author Information
1. 中南大学湘雅二医院泌外器官移植科
- Keywords:
Kidney transplantation;
Perfusion fluid;
Infection
- From:
Chinese Journal of Organ Transplantation
2018;39(3):135-139
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the distribution of microorganisms in kidney perfusion fluid and perirenal drainage of the renal allografts,and provide evidence to guide clinical practice.Methods The clinical data from the kidney donors and the recipients,the microbiologic culture results of kidney perfusion fluid and perirenal drainage were retrospectively analyzed.Results Ninety-one kidney perfusion fluid samples and 91 perirenal drainage samples were collected from 61 individual renal allografts,and 48 renal allografts were paired.Fourteen (15.4％,14/91) cultured kidney perfusion fluid samples were positive,17 strains were confirmed including 13 strains of bacteria and 4 strains of fungal,and 9 (69.2％,9/13) of bacterial strains were multidrug-resistance with 7 strains resistant to carbapenems,but there was no significant heterogeneity in the outcome of recipients with positive or negative culture results of kidney perfusion fluid samples.Eight (8.8％,8/91) perirenal drainage samples from different recipients were positive,5 of 8 bacterial strains were multidrug-resistance and 3 of them were resistant to carbapenems including meropenem or imipenern.There was no significant correlation between the length of donors' hospital stay and the culture results (P＞0.05),and there was also no significant correlation between the length of recipients' hospital stay after transplantation and the culture results (P＞0.05).Conclusion The kidney with positive perfusion fluid microbiologic culture can be transplanted safely using the prophylaxis or preemptive anti-infection therapy.
