Association of preoperative serum albumin level with clinicopathologic features and prognosis in gastric stump cancer
10.3760/cma.j.issn.1007-631X.2018.10.007
- VernacularTitle:术前血清白蛋白水平与残胃癌患者临床病理特征及预后的关系
- Author:
Shenghong WEI
1
;
Yi WANG
;
Zaisheng YE
;
Yi ZENG
;
Zhenmeng LIN
;
Zhitao LIN
;
Shu CHEN
;
Xiaoling CHEN
;
Luchuan CHEN
Author Information
1. 福建医科大学附属肿瘤医院福建省肿瘤医院胃肠外科福建省肿瘤医院外科研究室国家临床重点专科建设项目单位福建省肿瘤生物治疗重点实验室
- Keywords:
Stomach neoplasms;
Serum albumin;
Pathology,clinical;
Prognosis
- From:
Chinese Journal of General Surgery
2018;33(10):828-831
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinicopathologic characteristics and prognosis of gastric stump cancer in relation to serum albumin level.Methods The clinical data of 149 gastric stump cancer patients treated from Jan 1999 to Jun 2015 were analyzed.Patients were divided into normal serum albumin group (＞ 35 g/L,n =81) and group of hypoalbuminemia (≤ 35 g/L,n =68).Results Clinicopathologic characteristics,tumor size,depth of invasion,lymph node status and TNM stage were significantly different between the two groups (P ＜ 0.05).Univariate analysis showed that factors that influence prognosis were serum albumin level,tumor size,serosal invasion,tumor location and tumor curative resection rate (all P ＜ 0.05).Cox's proportional hazard regression model showed that serum albumin level and tumor curative resection rate were independent prognostic factors for survival,lymph node matastasis(2.2 ±4.3) vs.(4.1 ±4.4)were significantly different between the two groups (P ＜0.05).The overall 5-year survival rate was 44.1％.The 5-year survival rate were 54.0％ for normal albumin group and 32.2％ for hypoalbuminemic group,P =0.011.Conclusion Lower preoperative serum albumin level is associated with poorer prognosis in gastric stump cancer patients.
