Clinicopathological characteristics of differentiated thyroid carcinoma in 61 patients under 14 years old
10.3760/cma.j.issn.1007-631X.2018.09.013
- VernacularTitle:61例14岁以下儿童分化型甲状腺癌的临床病理特点
- Author:
Songfeng WEI
1
;
Ming GAO
;
Yigong LI
;
Yang YU
;
Xiangqian ZHENG
;
Chuanxiang HU
Author Information
1. 300060,天津医科大学肿瘤医院甲状腺颈部肿瘤科 国家肿瘤临床医学研究中心 天津市“肿瘤防治”重点实验室
- Keywords:
Thyroid neoplasms;
Child;
Diagnosis;
Therapy
- From:
Chinese Journal of General Surgery
2018;33(9):756-759
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinico-pathological characteristics and treatment of thyroid carcinoma in patients under 14 years old.Method The clinical and pathological data of 61 children 14 years old or younger treated for differentiated thyroid carcinoma (DTC) from Jan 2005 to Dec 2014 were retrospectively analyzed.Results There were 26 males and 35 females with the sex ratio of 1 ∶ 1.35.All the 61 patients underwent surgery including lobectomy for ipsilateral foci in 11 cases and total or near total thyroidectomy for bilateral or multi-foci in 50 cases.5 patients had not lymph node metastasis.56 patients had central compartment metastasis and 47 patients had lateral cervical lymph node metastasis.9 patients had distant metastasis and the affected organ was lung.Pathology for all the 61 patients was thyroid papillary carcinoma,35 patients were of highly invasive subtype.The median follow-up time was 3 years and 6 months (30-116 months) with a total survival rate of 100％ while 4 patients suffered from recurrence.Conclusions For below 14 years old DTC patients,the prognosis is better than in adults.The rate of bilateral lesions or multiple foci in ipsilateral lobe and central compartment lymph node or lateral neck lymph node metastasis was higher than in adults.Furthermore,highly invasively pathological subtype is more common in younger patients.
