Nonsentinel lymph nodal status in 1-2 sentinel lymph node positive early breast cancer patients
10.3760/cma.j.issn.1007-631X.2018.07.012
- VernacularTitle:前哨淋巴结1～2枚转移的早期乳腺癌患者非前哨淋巴结转移状态分析
- Author:
Dechuang JIAO
1
;
Jiujun ZHU
;
Jianghua QIAO
;
Lina WANG
;
Youzhao MA
;
Zhenduo LU
;
Zhenzhen LIU
Author Information
1. 450008,郑州大学附属肿瘤医院(河南省肿瘤医院)乳腺科
- Keywords:
Breast neoplasms;
Sentinel lymph node biopsy;
Z0011
- From:
Chinese Journal of General Surgery
2018;33(7):571-574
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the nonsentinel lymph nodal (NSLN) status in 1-2 sentinel lymph node positive early breast cancer and to compare with that in Z0011 ALND group.Methods A total of 234 T1,T2 invasive breast cancer with 1-2 positive sentinel lymph nodes were collected in Henan Tumorr Hospital from Jul 2010 to Aug 2014.The data was compared with that of Z0011 ALND group.Results 234 female patients were enrolled.76 cases had non sentinel lymph node metastases.The proportion of 1 and 2 sentinel lymph node metastases was 75.2％ and 24.8％,respectively.The number of positive sentinel lymph nodes and that of negative ones were independent predictors of the non sentinel lymph node status (all P ＜ 0.05).Menstrual status,hormone receptor,Ki67 level and HER2 were not associated with nonsentinel lymph node metastasis (all P ＞ 0.05).They had nonsentinel lymph node positive rate (P ＞ 0.05) similar to that of Z0011 ALND group.Conclusious The number of sentinel lymph nodes and negative sentinel lymph nodes were associated with nonsentinel lymph node metastasis in the 1-2 sentinel lymph positive early stage breast cancer.Those patients had similar positive nonsentinel lymph node rate to that of Z0011 ALND group.
