Endoscopic diagnosis for primary gastrointestinal mucosa-associated lymphoid tissue lymphoma and diffuse large B-cell lymphoma
10.3760/cma.j.issn.1007-631X.2018.06.015
- VernacularTitle:内镜对原发性胃肠道黏膜相关淋巴组织淋巴瘤和弥漫性大B细胞淋巴瘤的诊断价值
- Author:
Junbao GU
1
;
Xiaolin LI
;
Xuebin BAO
;
Zhao MA
Author Information
1. 河南省人民医院胃肠外科
- Keywords:
Lymphoma,B-cell,marginal zone;
Lymphoma,large B-cell,diffuse;
Endosonography
- From:
Chinese Journal of General Surgery
2018;33(6):493-496
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate endoscopy for the diagnosis of primary gastrointestinal mucosaassociated lymphoid tissue lymphoma (MALT lymphoma) and diffuse large B-cell lymphoma (DLBCL).Methods The clinical pathology,hematological/biochemical studies,and endoscopic data of 98 primary gastrointestinal MALT lymphoma and DLBCL patients from Aug 2010 to May 2017 were analyzed retrospectively.Results 17 patients had higher than normal LDH blood level (＞270 U/L).47 patients were Helicobacter pylori (Hp) positive;Gastrointestinal endoscopic study,including endoscopic mucosal resection (EMR)/endoscopic submucosal dissection (ESD) and endoscopic ultrasonography established diagnosis of MALT lymphoma and DLBCL in 96 out of 98 cases (98％).The endoscopic manifestations of MALT lymphoma and DLBCL were ulcerative,uplift,diffuse and infiltrative,and erosive,with ulcerative type as the dominant one.The follow-up examination showed that the survival ratio (88％) of MALT patients was higher than that of DLBCL(68％),and more patients with lower Ann Arbor stage survived (92％) than those with higher Ann Arbor stage (64％).Conclusion Endoscopic biopsy together with endoscopic ultrasonography makes definite diagnosis of MALT and DLBCL.
