Liver transplantation using donation after cardiac death: A single-center experience of 115 cases
10.3760/cma.j.issn.1007-631X.2018.06.012
- VernacularTitle:单中心心脏死亡器官捐献肝移植115例分析
- Author:
Changjiang LU
1
;
Caide LU
;
Shengdong WU
;
Jing HUANG
;
Yongfei HUA
;
Jiongze FANG
;
Gaoqing WANG
;
Wei JIANG
;
Min WANG
Author Information
1. 宁波市医疗中心李惠利东部医院肝胆胰外科宁波市肝移植中心
- Keywords:
Liver transplantation;
Postoperative complications
- From:
Chinese Journal of General Surgery
2018;33(6):482-485
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical outcomes of liver transplantation by using donation after cardiac death (DCD) in single center.Methods The clinical data of 115 DCD donors and recipients of liver transplantation from Jan 2012 to Sep 2017 at our institution were analyzed,including preoperative general data,intraoperative status,and postoperative early complications.Patients were followed up to Oct 30th,2017.The measurement data with normal distribution were analyzed by t test,the enumeration data were analyzed by chi-square test or Fisher exact probability test,and the Kaplan-Meier method was used for survival analysis.Results All of the 115 donors were within China category Ⅲ using the classification of China donor after cardiac death.Donor graft mean warm ischemic time and cold ischemic time was (10 ± 4) min and (6.1 ± 1.7) h,respectively.All of the recipients underwent liver transplantation successfully.The mean preoperation MELD score was 14 ± 7.Seven patients were ABO-incompatible liver transplantation (A→O,3 cases,B→O 2 cases,AB→O 1 case,AB→A 1 case).19 patients (16.5％) had postoperative complications (Clavien-Dindo classification grade Ⅲ-Ⅴ).The perioperative mortality was 2.6％ (3 cases).All patients were followed up for an average (21 ± 17) mon.Patients 1-,3-,and 5-year survival rates were 93.6％,81.8％,and 77.5％,respectively.Conclusion The outcome of DCD liver transplantation is favorable at our institution under careful donor and recipient selection and intensive perioperative management.
