The impact of lymph node metastasis on the prognosis of postoperative pancreatic carcinoma
10.3760/cma.j.issn.1007-631X.2018.06.003
- VernacularTitle:淋巴结转移对胰腺癌患者预后的影响
- Author:
Kai CHEN
1
;
Hongji YANG
;
Xiaofan DENG
;
Yu ZHANG
;
Shikai ZHU
;
Ji ZHAO
;
Xingchao LIU
;
Yunfei CHEN
Author Information
1. 四川省医学科学院·四川省人民医院器官移植中心
- Keywords:
Pancreatic neoplasms;
Pathology,clinical;
Lymphatic metastasis;
Prognosis
- From:
Chinese Journal of General Surgery
2018;33(6):452-455
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate clinicopathological features of pancreatic carcinoma with or without lymph node metastasis,and to explore the relationship between the lymph node metastasis and the prognosis of pancreatic carcinoma.Methods The clinical and follow up data of 216 patients with pancreatic carcinoma from 2001 to 2015 were retrospectively analyzed.Kaplan-Meier method was used to estimate survival rates and plot survival curves.Results The postoperative survival time was 4-86 months,the median survival time was 19 months,and the postoperative 1,3 and 5 year survival rates were 65.1％,33.8％,20.5％,respectively.Patients with positive lymph node metastasis were with 1,3,5 year survival rates of 36.5％,12.2％,0％,those with no lymph node metastasis were with 1,3,5 year survival rates of 70.3％,38.0％,21.4％ (x2 =15.803,P ＜ 0.001).Conclusions Lymph node metastasis in patients with pancreatic cancer is worse than that without lymph node metastasis.Lymph node metastasis is one of the main prognostic factors in patients after radical resection of the pancreatic cancer.
