Risk factors predicting conservative treatment failure of acute calculous cholecystitis in pregnant women

VernacularTitle:预测妊娠期急性结石性胆囊炎保守治疗无效的早期危险因素
Author: Sunbing XU ¹ ; Jingrui WANG ; Yang CAI ; Bei LU ; Qijun YANG
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1. 杭州市第一人民医院南京医科大学附属杭州医院肝胆胰外科
Keywords: Cholecystitis,acute; Choleystolithiasis; Pregnancy; Risk factors
From: Chinese Journal of General Surgery 2018;33(5):381-384
CountryChina
Language:Chinese
Abstract: Objective To explore the predictor of invalid conservative treatment of acute calculous cholecystitis (ACC) in pregnant women.Methods A total of 107 pregnant patients with ACC in a tertiary hospital from Jan.2010 to Jun.2017 were studied retrospectively.Results Univariate analysis revealed that body temperature ＞ 37.3 ℃ (x2 =4.721,P ＜ 0.05),gallbladder dilation (x2 =4.764,P ＜ 0.05),TBiL (t=-2.518,P＜0.05),ALT (t=-2.860,P＜0.05),AST (t=-3.014,P＜0.05),hospital stay (x2 =9.769,P ＜ 0.05),rate of pregnancy termination (x2 =7.349,P ＜ 0.05) were all significantly higher in conservative therapy failure group than those in the conservative therapy success group.Multivariate analysis showed that gallbladder dilation,TBiL,body temperature ＞ 37.3 ℃,AST were the independent risk factors predicting invalid conservative management.Conclusion Gallbladder dilation,body temperature ＞ 37.3 ℃,high level of TBiL and AST are the early predictors for the invalid conservative management for ACC in pregnant women.