Clinical characteristics and prognostic factors of primary gastric lymphoma

VernacularTitle:原发性胃淋巴瘤的临床病理特点及预后影响因素
Author: Min ZHAI ¹ ; Haitao ZHANG ; Yunliang WANG ; Fei WANG ; Xiaogang ZHOU ; Qiaoming ZHI ; Jin ZHOU
Author Information

1. 苏州大学附属第一医院普外科
Keywords: Lymphoma; Pathology,clinical; Prognosis
From: Chinese Journal of General Surgery 2018;33(3):232-234
CountryChina
Language:Chinese
Abstract: Objective To explore the clinical characteristics and prognostic factors of primary gastric lymphoma.Methods Clinical data of 78 primary gastric lymphoma patients treated between September 2012 and January 2017 in our hospital were analyzed retrospectively.Results 1-year and 3-year survival rate were 86％ and 68％ respectively.Univariate analysis showed that the four factors including the level of serum lactate dehydrogenase (x2 =35.088,P =0.000),Musshoff stage (x2 =29.930,P =0.000),pathology types (x2 =6.077,P =0.014),IPI score (x2 =21.337,P =0.000) were associated with the prognosis.Multivariate analysis showed that Musshoff stage was an independent risk factor for the prognosis when stage Ⅰ,stage Ⅱ (OR =1.075,95％ CI:0.060-19.107,P =0.961) were compared with stageⅢ (OR =11.994,95％ CI:1.042-138.083,P =0.046),or stage Ⅳ (OR =13.165,95％ CI:1.476-117.417,P =0.021).Conclusions Musshoff stage is an independent factor for the prognosis,surgical treatment can not prolong survival and chemotherapy is the therapy of choice.