Paclitaxel coated balloon versus plain balloon angioplasty in treating popliteal arteriosclerosis occlusive disease
10.3760/cma.j.issn.1007-631X.2017.12.013
- VernacularTitle:紫杉醇药物涂层球囊与普通球囊治疗腘动脉粥样硬化闭塞性病变的疗效比较
- Author:
Tong ZHANG
1
;
Baixi ZHUANG
;
Bo SHI
;
Miao YANG
;
Chunli YU
;
Lubo MA
Author Information
1. 中国中医科学院西苑医院血管外科
- Keywords:
Arteriosclerosis;
Popliteal artery;
Angioplasty;
Restenosis
- From:
Chinese Journal of General Surgery
2017;32(12):1026-1029
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the short-term clinical results of paclitaxel coated balloon angioplasty (PCBA) and plain balloon angioplasty (POBA) in remedying popliteal arteriosclerosis occlusive disease.Methods From July 2013 to July 2016,56 patients of severe intermittent claudication or critical limb ischemia (CLI) due to stenosis or occlusion of popliteal artery were treated by PCBA in 30 patients (30 limbs),and by POBA in 26 patients (26 limbs).We compared clinical data of both groups at 1,3 and 6 months.Results The mean(± SD)length of treated segment in PCBA and POBA group respectively was (8.6 ± 3.3) cm and (6.9 ± 3.7) cm (t =1.817,P ＞ 0.05).According to peak systolic velocity rate (PSVR ＞ 2.4 as restenosis),l-month,3-month and 6-month restenosis rates were 0 (0 patients)in PCBA group vs.11.5％ (3 patients)in POBA group(x2 =1.74,P ＞0.05),0(0 patients)vs.24.0％ (6 patients) (x2 =5.59,P ＜ 0.05),3.6％ (1 patients)vs.65.2％ (15 patients) (x2 =22.29,P ＜ 0.01),respectively.6-month target lesion revascularization(TLR) was 3.6％ (1 patient) in PCBA group vs.60.9％ (in 14 patients) in POBA group(x2 =19.97,P ＜0.01),limb salvage rate at 6 months was 100％ (28 patients)vs.65.2％ (15 patients) (x2 =11.55,P ＜ 0.01).Conclusion In the short term,paclitaxel coated balloon angioplasty was superior to POBA for anti-restenosis of popliteal arteriosclerosis occlusive disease.
