Correlation between the elevation of D-dimer and of deep venous thrombosis progression of the lower extremities after abdominal surgery
10.3760/cma.j.issn.1007-631X.2017.12.012
- VernacularTitle:D-二聚体升高临界值与腹部手术术后下肢深静脉血栓进展的相关性研究
- Author:
Yongshun GAO
1
;
Xizhong YAN
;
Jingjing HUANG
;
Peng CHEN
;
Yunfei ZHANG
;
Xiaojin FAN
;
Jiangang SUN
;
Yiming WANG
Author Information
1. 450000,郑州大学第一附属医院胃肠外科
- Keywords:
Venous thrombosis;
Perioperative period;
D-dimer;
Intermuscular vein thrombosis
- From:
Chinese Journal of General Surgery
2017;32(12):1022-1025
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of D-dimer in predicting the progression of lower extremity deep venous thrombosis (DVT) during perioperative period of gastrointestinal surgery.Methods Color Doppler ultrasound was used to dynamically monitor the formation and changes of perioperative deep venous thrombosis (DVT) in 239 patients receiving abdominal surgery in our department from Nov 2014 to Aug 2016.Changes of plasma D-dimer were measured,and clinical data of malignant tumor,infection,age,BMI were collected.The relationship between D-dimer elevation and DVT progression was analyzed.Results Lower extremity DVT after surgery developed in 97 patients,and thrombosis progression occurred in 16.6％ (16/97).Univariate logistic regression analysis showed that continuous increase of postoperative D-dimer was closely related to the progression of thrombosiss.Multivariate Logistic regression analysis showed that the continuous rise of D-dimer was an independent risk factor for thrombosis.ROC curve analysis showed significantly increased risk of thrombosis progression,when plasma D-dimer polymerization increased ＞0.87 mg/L on the 3rd day.Conclusion The continuous increase of D-dimer ＞ 0.87 mg/L predicts DVT progression of lower extremity DVT.
