Clinical and pathological analysis of three cases of lichen planopilaris

VernacularTitle:毛发扁平苔藓三例分析
Author: Ting SU ¹ ; Yiwen CHEN ; Yaqi SUN ; Meihua ZHANG ; Zhonglan SU
Author Information

1. 210029,南京医科大学第一附属医院江苏省人民医院皮肤科
Keywords: Lichen planus; Hair; Hair follicle; Alopecia
From: Chinese Journal of Dermatology 2018;51(8):599-600
CountryChina
Language:Chinese
Abstract: Objective To investigate clinical and histopathological features of lichen planopilaris (LPP).Methods The clinical and histopathological findings in 3 cases of LPP were analyzed.Results All the 3 patients were female,and their average age was 49 years.One patient presented with large-area patchy hair loss on the frontal,parietal and occipital region,and 2 patients presented with irregular patchy hair loss on the scalp and skin atrophy.Besides the hair loss,the eyebrows and axillary hairs also lost in 1 patient.Histopathological examination showed liquefaction degeneration of basal cells in the walls of hair follicles and infiltration of lymphocytes.Infiltration of a small number of lymphocytes was also observed around blood vessels and appendages.Conclusions LPP may only affect the scalp,or involve the other sites all over the body.LPP commonly manifests as patchy hair loss on the scalp and skin atrophy,and is pathologically characterized by liquefaction degeneration of basal cells in hair follicles and infiltration of lymphocytes.