Effect of azone on transdermal absorption of 6-gingerol
10.3969/j.issn.1001-1528.2018.03.014
- VernacularTitle:氮酮对6-姜酚透皮吸收的影响
- Author:
Quan SUN
1
;
Bing LI
;
Xing WANG
;
Yan ZHU
;
Xing-Hao WANG
;
Zai-Xing CHEN
Author Information
1. 中国医科大学药学院
- Keywords:
azone;
6-gingerol;
transdermal absorption
- From:
Chinese Traditional Patent Medicine
2018;40(3):583-586
- CountryChina
- Language:Chinese
-
Abstract:
AIM To study the effect of azone on transdermal absorption of 6-gingerol.METHODS In vitro transdermal diffusion test was performed by TP-6 horizontal diffusion pool.In vitro rat skins were selected as permeation barrier,the effects of different concentrations of ethanol and azone on permeation performance of 6-gingerol were investigated.RESULTS Both 30％ ethanol and 3％ azone contributed to the significant permeation enhancement of 6-gingerol.CONCLUSION This research can provide reference for the preparation of transdermal drug delivery systems containing 6-gingerol.
