Correlation of transcutaneous oxygen pressure and blood lactate in patients with septic shock
10.3760/cma.j.issn.0578-1426.2018.11.009
- VernacularTitle:感染性休克患者经皮氧分压与血乳酸的相关性
- Author:
Liang XU
1
;
Jing YAN
;
Shijin GONG
;
Cong YE
;
Minjia WANG
;
Haiwen DAI
Author Information
1. 浙江医院重症医学科
- Keywords:
Shock septic;
Transcutaneous oxygen pressure;
Tissue perfusion;
Lactic acid
- From:
Chinese Journal of Internal Medicine
2018;57(11):841-843
- CountryChina
- Language:Chinese
-
Abstract:
To analyze the correlation between transcutaneous oxygen pressure (PtcO2) and blood lactate in patients with septic shock. Fifty-sixpatients with septic shock were prospectively investigated. PtcO2 was monitored continuously for 6 hours, and arterial blood gas was measured at baseline (T0) and 6 hours (T6). Records of PtcO2, were analyzed for the correlation with lactate level and lactate clearance rate. PtcO2 valuesin the high lactate clearance group and the low one were compared.The lowest value of PtcO2 at T6 and duration of PtcO2<40 mmHg (1 mmHg=0.133 kPa) were both correlated with lactate level and lactate clearance rateat T6. The low predictive value of PtcO2 was 29 mmHg of lactate clearance under 20%with a sensitivity 85.2%and a specificity 65.5%. The low predictive value of PtcO2 in high lactate clearance group was significantly higher than that in low lactate clearance group, while the duration of PtcO2<40 mmHg was shorter than the latter. During 6 h continuous monitoring, patients with a significant low PtcO2 or prolonged duration of low PtcO2 have relatively high lactate or low lactate clearance after resuscitation.