The influence of gender on clinical manifestations of primary hyperparathyroidism
10.3760/cma.j.issn.0578-1426.2018.10.011
- VernacularTitle:性别对原发性甲状旁腺功能亢进症患者临床表现的影响
- Author:
Tao JIANG
1
;
Xiaoai YAO
;
Bojun WEI
;
Hong CHANG
Author Information
1. 100038,首都医科大学附属北京世纪坛医院内分泌科
- Keywords:
Primary hyperparathyroidism;
Sex;
Clinical features
- From:
Chinese Journal of Internal Medicine
2018;57(10):753-755
- CountryChina
- Language:Chinese
-
Abstract:
To explore the impact of gender on presentation of primary hyperparathyroidism (PHPT), clinical data of 150 histopathologically proven PHPT patients were collected and retrospectively analyzed. Most of the patients (72.0％) were parathyroid adenoma (PA), and 9.3％of them were parathyroid carcinoma (PC). In PA patients, albumin-corrected serum calcium levels (TASC) were lower in women than in men [(2.84±0.28)mmol/L vs.(3.03±0.34)mmol/L, P=0.006 ]. In all PHPT subjects, serum urea nitrogen, creatinine, uric acid levels were lower in women than in men. Bone pain was more frequent in women over 50 years old than in men (52.33％vs.29.17％, P=0.045). The incidence of PC was higher in men than in women (20.59％ vs. 6.03％, P=0.010). In conclusion, there are gender differences in the clinical presentation of PHPT. TASC was high in men with PA compared to women with PA. Bone pain was more common in the woman patients over 50 years old, and PC was more common in men.
