Expert consensus on the diagnosis and treatment of cryptococcal meningitis
10.3760/cma.j.issn.0578-1426.2018.05.003
- VernacularTitle:隐球菌性脑膜炎诊治专家共识
- Author:
Zhengyin LIU
1
;
Guiqiang WANG
;
Liping ZHU
;
Xiaoju LYU
;
Qiangqiang ZHANG
;
Yunsong YU
;
Zhihui ZHOU
;
Yanbin LIU
;
Weiping CAI
;
Ruoyu LI
;
Wenhong ZHANG
;
Fujie ZHANG
;
Hao WU
;
Yingchun XU
;
Hongzhou LU
;
Taisheng LI
Author Information
1. 100730,中国医学科学院北京协和医学院北京协和医院感染内科
- Keywords:
Meningitis,cryptococcal;
Diagnosis;
Treatment
- From:
Chinese Journal of Internal Medicine
2018;57(5):317-323
- CountryChina
- Language:Chinese
-
Abstract:
Cryptococcal meningitis is a common and refractory central nervous system infection,with high rates of mortality and disability.The experts of the Society of Infectious Diseases of Chinese Medical Association have reached this consensus after a thorough discussion.Based on the current situation of cryptococcal meningitis in China,the management of cryptococcal meningitis includes 6 aspects:introduction,microorganism identification,clinical manifestations and diagnosis,principles of antifungal therapy,treatment of refractory and recurrent meningitis,treatment of intracranial hypertension.There is not a separate consensus on human immunodeficiency virus (HIV) infection in patients with cryptococcal meningitis.This article focuses on different antifungal regimens and reducing intracranial pressure by reference to Infectious Disease Society of America (IDSA) guidelines.The importance of early diagnosis,combined long-term antifungal therapy,control of intracranial hypertension are emphasized.
