Expression levels of serum tenascin-C in type 2 diabetes mellitus patients with different excretion rates of urinary albumin and its clinical significance
10.3760/cma.j.issn.1000-6699.2018.11.007
- VernacularTitle:糖尿病患者血清腱生蛋白C与尿白蛋白排泄率相关关系的研究
- Author:
Yang ZHOU
1
;
Yao XU
;
Huiwen REN
;
Yili WANG
;
Binbin ZHU
;
Qiuyue WANG
Author Information
1. 中国医科大学附属第一医院内分泌与代谢病科
- Keywords:
Diabetic mellitus;
Tenascin-C;
Osteopontin;
Transforming growth factor-β1
- From:
Chinese Journal of Endocrinology and Metabolism
2018;34(11):931-934
- CountryChina
- Language:Chinese
-
Abstract:
The expression levels of serum tenascin-C, osteopontin(OPN), and transforming growth factor-β1(TGF-β1) in the patients of diabetic mellitus were measured by ELISA. With the increase of the UACR, the expression of tenascin-C, osteopontin, and transforming growth factor-β1 showed a trend of increase and hypertension will argument this phenomenon. Pearson correlation analysis showed that levels of tenascin-C were positively correlated with HbA1C , body mass index, systolic blood pressure, diastolic blood pressure, UACR, osteopontin, and transforming growth factor-β1.
