Investigation the prevalence and risk factors of vertebral fracture in community-dwelling elderly in Shanghai
10.3760/cma.j.issn.1000-6699.2018.06.009
- VernacularTitle:上海社区老年人椎体骨折的患病率与危险因素分析
- Author:
Wenjing TANG
1
;
Wei HONG
;
Minmin CHEN
;
Yanping DU
;
Huilin LI
;
Songbai ZHENG
;
Qun CHENG
Author Information
1. 200040上海,复旦大学附属华东医院骨质疏松科,上海市老年医学研究所骨代谢研究室,复旦大学老年医学中心
- Keywords:
Vertebral fractures;
Prevalence;
Risk factors;
Community-dwelling elderly
- From:
Chinese Journal of Endocrinology and Metabolism
2018;34(6):498-504
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence and risk factors of vertebral fractures in the elderlys in Shanghai community. Methods Stratified sampling was performed according to the age distribution of the population in 3 urban and 2 suburban communities in Shanghai, and a total of 2 929 old people aged over 65 years were enrolled. The thoracic and lumbar radiographs and questionnaires were obtained in all the participants. The diagnosis of vertebral fractures were evaluated using Genant′s semi-quantitative method, and the prevalence of vertebral fracture was calculated. Logistic regression was used to analyze the risk factors of vertebral fracture. Results ( 1) The prevalence of vertebral fractures in community-dwelling elderly was 14.4%totally,and 20.1%in individuals above 80 years old,which was significantly higher than the others (P<0.05). The prevalence of vertebral fractures in females was significantly higher than that in males (18.5%vs 12.4%, P<0.05). (2) The most common vertebral fracture sites were T12 and L1. Grade 1 vertebral fracture was most common in our cohort. The proportions of grade 2 and grade 3 were significant higher in females than that in males (30.6% vs 17.0%, P<0.05). (3) Gender and sex had an interaction effect on the prevalence of vertebral fractures. Prevalence of vertebral fractures increased steadily with age in both genders, although the gradient was steeper for women (P<0.001). (4) Logistic regression analysis showed that: female, age, parental hip fracture history, previous fracture history, and alcohol consumption were risk factors of vertebral fractures in community elderly. Smoking, long-term use of glucocorticoid, various diseases associated with secondary osteoporosis had no significant correlation with vertebral fracture. Conclusion The vertebral fractures were more common and serious in women than in men in community elderly. Age was significantly correlated with the presence of vertebral fracture in women than that in men. Female, age, parental hip fracture history, previous fracture history, and alcohol consumption were risk factors of vertebral fractures in community elderlys.
