Related factor analysis for persistent severe hypocalcemia after parathyroidectomy in secondary hyperparathyroidism patients

VernacularTitle:继发性甲状旁腺功能亢进患者术后持续性严重低钙血症的相关因素分析
Author: Heng GU ¹ ; Xiaoping GENG ; Jiangming CHEN ; Shengxue XIE
Author Information

1. 安徽医科大学第二附属医院普外科
Keywords: Persistent severe hypocalcemia; Secondary hyperparathyroidism; Parathyroidectomy
From: Chinese Journal of Endocrinology and Metabolism 2018;34(1):57-60
CountryChina
Language:Chinese
Abstract: Retrospective analysis of clinical data was conducted in the patients with secondary hyperparathyroidism( SHPT) undergone parathyroidectomy ( PTX ) in our department from September 2015 to September 2016. Uni- and multivariate analyses were conducted to define independent influencing factors for persistent severe hypocalcemia. The results showed that 27 cases(31％ ) suffered from persistent severe hypocalcemia in a total of 87 patients. Univariate analysis revealed that age, weight, hospitalization time after operation, the year of increased serum creatinine, preoperative alkaline phosphatase ( ALP), preoperative intact parathyroid hormone (iPTH), preoperative albumin, postoperative 1 d serum calcium and phosphorus level, renal hypertension, and degeneration of bone were risk factors of persistent severe hypocalcemia. Multivariate analysis revealed that the year of increased serum creatinine, preoperative ALP, and preoperative albumin were the independent influence factors for persistent severe hypocalcemia.